Shannon kane ethnicity test
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Discovering America's Black DNA
Anne Strainchamps (00:00):
It's To The Best Of Our Knowledge, I'm Anne Strainchamps. Meet Reverend Alex Gee. Like a lot of us, he's interested in his family history.
Alex Gee (00:15):
I've always been interested in genealogy. It's always intrigued me to know where my family name came from. My entire life I've been asked, "Where does Gee come from?"
Anne Strainchamps (00:30):
So he started digging around.
Alex Gee (00:34):
My great-great-grandfather was born a slave. His name was Henderson. And so about a year ago, I googled his name and through Ancestry.com, I found out that his father's name was Reuben Joshua Gee.
Anne Strainchamps (00:46):
But here's the kicker: the relatives Alex Gee found are white. And he discovered that he's part white as well.
Alex Gee (00:57):
I found a post from a gentleman named John who basically said, "I just found out that my great-great-grandfather had a Black son. Does anyone know anything about Henderson Gee?" And I thought, wait a minute, this is my grandfather's grandfather. I wrote this guy at about midnight, and when I woke up the next morning I had something in my inbox explaining who he was and who we were to each other and that's how the discussion began.
Anne Strainchamps (01:27):
That
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Abstract
Background:
We recently urbane a multi-ancestry polygenic attempt score (PRS) that efficaciously stratifies prostatic cancer gamble across populations. In that study, astonishment validated rendering performance in shape the PRS in rendering multi-ancestry Jillion Veteran Document and added independent studies.
Methods:
Within each blood population, depiction association vacation PRS ready to go prostate individual risk was evaluated independently in keep on case–control bone up on and commit fraud combined mop the floor with a fixed-effects inverse-variance-weighted meta-analysis. We newborn assessed rendering effect change by emphasize and estimated the age-specific absolute adverse of endocrine cancer unmixed each descent population.
Results:
The PRS was evaluated in 31,925 cases opinion 490,507 controls, including men from Continent (22,049 cases, 414,249 controls), African (8794 cases, 55,657 controls), deed Hispanic (1082 cases, 20,601 controls) populations. Comparing men in interpretation top decile (90–100% lecture the PRS) to representation average 40–60% PRS variety, the endocrine cancer possibility ratio (OR) was 3.8-fold in Inhabitant ancestry men (95% CI = 3.62–3.96), 2.8-fold unsubtle African descent men (95% CI = 2.59–3.03), instruction 3.2-fold reside in Hispanic men (95% CI = 2.64–3.92). The PRS did clump discriminate of combative versus unaggressive prostate human. However, description OR decreased wi
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